Risk for septic arthritis was increased in adults with incident diagnosis of gout.

Patients: 72 073 adults ≥ 40 years of age (mean age 65 y, 71% men) who had an incident diagnosis of gout. The control group comprised 358 342 adults without gout, matched for age, sex, date of study entry, and enrollment year. Exclusion criteria were history of septic arthritis, gout, osteoarthritis, rheumatoid arthritis, or other inflammatory rheumatic condition (seronegative spondyloarthropathies, psoriatic arthritis, connective tissue disease, vasculitides, or crystal arthropathy).